the researchers discovered that in osteoarthritis, the expression of the polyadenylation factor CPSF4 associated with synovial inflammation is increased. CPSF4 and another polyadenylation factor are required for activation of key inflammatory cell macrophages. Administration of cordycepin inhibits the activity of polyadenylation factors in macrophages and inhibits the inflammatory response. Cordycepin treatment reduces pain behavior and structural damage in osteoarthritic rats and mice and supports the role of polyadenylation in the progression of osteoarthritis and inflammatory gene expression.
GLUCOSAMINE IS VERY EFFECTIVE TONIC FOR JOINTS RELIEF
Boswellia is an effective anti-inflammatory, it can be an effective painkiller and may prevent the loss of cartilage.